CovidFranceV1, Main, Exploration, bibRecord, 001397

Caring for patients with cancer in the COVID-19 era.

Identifieur interne : 001397 ( Main/Exploration ); précédent : 001396; suivant : 001398

Caring for patients with cancer in the COVID-19 era.

Auteurs : Joris Van De Haar [Pays-Bas] ; Louisa R. Hoes [Pays-Bas] ; Charlotte E. Coles [Royaume-Uni] ; Kenneth Seamon [Royaume-Uni] ; Stefan Fröhling [Allemagne] ; Dirk J Ger [Allemagne] ; Franco Valenza [Italie] ; Filippo De Braud [Italie] ; Luigi De Petris [Suède] ; Jonas Bergh [Suède] ; Ingemar Ernberg [Suède] ; Benjamin Besse [France] ; Fabrice Barlesi [France] ; Elena Garralda [Espagne] ; Alejandro Piris-Giménez [Espagne] ; Michael Baumann [Allemagne] ; Giovanni Apolone [Italie] ; Jean Charles Soria [France] ; Josep Tabernero [Espagne] ; Carlos Caldas [Royaume-Uni] ; Emile E. Voest [Pays-Bas]

Source :

Nature medicine [ 1546-170X ] ; 2020.

RBID : pubmed:32405058

Descripteurs français

KwdFr :
- Betacoronavirus (MeSH), Humains (MeSH), Infections à coronavirus (complications), Infections à coronavirus (prévention et contrôle), Infections à coronavirus (épidémiologie), Pandémies (prévention et contrôle), Pneumopathie virale (complications), Pneumopathie virale (prévention et contrôle), Pneumopathie virale (épidémiologie), Prestations des soins de santé (MeSH), Soins ambulatoires (statistiques et données numériques), Tumeurs (complications), Tumeurs (thérapie).
MESH :
- prévention et contrôle : Infections à coronavirus, Pandémies, Pneumopathie virale.
- statistiques et données numériques : Soins ambulatoires.
- thérapie : Tumeurs.
- épidémiologie : Infections à coronavirus, Pneumopathie virale.
- complications : Betacoronavirus, Humains, Infections à coronavirus, Pneumopathie virale, Prestations des soins de santé, Tumeurs.

English descriptors

KwdEn :
- Ambulatory Care (statistics & numerical data), Betacoronavirus (MeSH), Coronavirus Infections (complications), Coronavirus Infections (epidemiology), Coronavirus Infections (prevention & control), Delivery of Health Care (MeSH), Humans (MeSH), Neoplasms (complications), Neoplasms (therapy), Pandemics (prevention & control), Pneumonia, Viral (complications), Pneumonia, Viral (epidemiology), Pneumonia, Viral (prevention & control).
MESH :
- complications : Coronavirus Infections, Neoplasms, Pneumonia, Viral.
- epidemiology : Coronavirus Infections, Pneumonia, Viral.
- prevention & control : Coronavirus Infections, Pandemics, Pneumonia, Viral.
- statistics & numerical data : Ambulatory Care.
- therapy : Neoplasms.
- Betacoronavirus, Delivery of Health Care, Humans.

Abstract

The current COVID-19 pandemic challenges oncologists to profoundly re-organize oncological care in order to dramatically reduce hospital visits and admissions and therapy-induced immune-related complications without compromising cancer outcomes. Since COVID-19 is a novel disease, guidance by scientific evidence is often unavailable, and impactful decisions are inevitably made on the basis of expert opinions. Here we report how the seven comprehensive cancer centers of Cancer Core Europe have organized their healthcare systems at an unprecedented scale and pace to make their operations 'pandemic proof'. We identify and discuss many commonalities, but also important local differences, and pinpoint critical research priorities to enable evidence-based remodeling of cancer care during the COVID-19 pandemic. Also, we discuss how the current situation offers a unique window of opportunity for assessing the effects of de-escalating anticancer regimens, which may fast-forward the development of more-refined and less-toxic treatments. By sharing our joint experiences, we offer a roadmap for proceeding and aim to mobilize the global research community to generate the data that are critically needed to offer the best possible care to patients.

DOI: 10.1038/s41591-020-0874-8
PubMed: 32405058

Affiliations:

Links toward previous steps (curation, corpus...)

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Le document en format XML

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<author><name sortKey="Ernberg, Ingemar" sort="Ernberg, Ingemar" uniqKey="Ernberg I" first="Ingemar" last="Ernberg">Ingemar Ernberg</name>
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<author><name sortKey="Besse, Benjamin" sort="Besse, Benjamin" uniqKey="Besse B" first="Benjamin" last="Besse">Benjamin Besse</name>
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<author><name sortKey="Barlesi, Fabrice" sort="Barlesi, Fabrice" uniqKey="Barlesi F" first="Fabrice" last="Barlesi">Fabrice Barlesi</name>
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<affiliation wicri:level="3"><nlm:affiliation>Aix Marseille University, CNRS, INSERM, CRCM, Marseille, France.</nlm:affiliation>
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<author><name sortKey="Garralda, Elena" sort="Garralda, Elena" uniqKey="Garralda E" first="Elena" last="Garralda">Elena Garralda</name>
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<author><name sortKey="Piris Gimenez, Alejandro" sort="Piris Gimenez, Alejandro" uniqKey="Piris Gimenez A" first="Alejandro" last="Piris-Giménez">Alejandro Piris-Giménez</name>
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<wicri:regionArea>Department of Medical Oncology, Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology, Barcelona</wicri:regionArea>
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<author><name sortKey="Baumann, Michael" sort="Baumann, Michael" uniqKey="Baumann M" first="Michael" last="Baumann">Michael Baumann</name>
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<wicri:regionArea>German Cancer Consortium, Heidelberg</wicri:regionArea>
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<affiliation wicri:level="3"><nlm:affiliation>German Cancer Research Center, Heidelberg, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Cancer Research Center, Heidelberg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
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<author><name sortKey="Apolone, Giovanni" sort="Apolone, Giovanni" uniqKey="Apolone G" first="Giovanni" last="Apolone">Giovanni Apolone</name>
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<author><name sortKey="Soria, Jean Charles" sort="Soria, Jean Charles" uniqKey="Soria J" first="Jean Charles" last="Soria">Jean Charles Soria</name>
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<country xml:lang="fr">France</country>
<wicri:regionArea>Gustave Roussy Cancer Campus, Villejuif</wicri:regionArea>
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<author><name sortKey="Tabernero, Josep" sort="Tabernero, Josep" uniqKey="Tabernero J" first="Josep" last="Tabernero">Josep Tabernero</name>
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<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Department of Medical Oncology, Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology, Barcelona</wicri:regionArea>
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<author><name sortKey="Caldas, Carlos" sort="Caldas, Carlos" uniqKey="Caldas C" first="Carlos" last="Caldas">Carlos Caldas</name>
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<wicri:regionArea>Cancer Research UK Cambridge Cancer Center, Cambridge</wicri:regionArea>
<wicri:noRegion>Cambridge</wicri:noRegion>
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<affiliation wicri:level="4"><nlm:affiliation>Department of Oncology and Cancer Research UK Cambridge Institute, Li Ka Shing Center, University of Cambridge, Cambridge, UK. carlos.caldas@cruk.cam.ac.uk.</nlm:affiliation>
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<wicri:regionArea>Department of Oncology and Cancer Research UK Cambridge Institute, Li Ka Shing Center, University of Cambridge, Cambridge</wicri:regionArea>
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<placeName><settlement type="city">Cambridge</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Angleterre de l'Est</region>
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<author><name sortKey="Voest, Emile E" sort="Voest, Emile E" uniqKey="Voest E" first="Emile E" last="Voest">Emile E. Voest</name>
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<wicri:regionArea>Division of Molecular Oncology & Immunology, The Netherlands Cancer Institute, Amsterdam</wicri:regionArea>
<placeName><settlement type="city">Amsterdam</settlement>
<region nuts="2" type="province">Hollande-Septentrionale</region>
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<affiliation wicri:level="3"><nlm:affiliation>Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands. e.voest@nki.nl.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Oncode Institute, The Netherlands Cancer Institute, Amsterdam</wicri:regionArea>
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</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Oncode Institute, The Netherlands Cancer Institute, Amsterdam</wicri:regionArea>
<placeName><settlement type="city">Amsterdam</settlement>
<region nuts="2" type="province">Hollande-Septentrionale</region>
</placeName>
</affiliation>
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<author><name sortKey="Coles, Charlotte E" sort="Coles, Charlotte E" uniqKey="Coles C" first="Charlotte E" last="Coles">Charlotte E. Coles</name>
<affiliation wicri:level="1"><nlm:affiliation>Cancer Research UK Cambridge Cancer Center, Cambridge, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Cancer Research UK Cambridge Cancer Center, Cambridge</wicri:regionArea>
<wicri:noRegion>Cambridge</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Seamon, Kenneth" sort="Seamon, Kenneth" uniqKey="Seamon K" first="Kenneth" last="Seamon">Kenneth Seamon</name>
<affiliation wicri:level="1"><nlm:affiliation>Cancer Research UK Cambridge Cancer Center, Cambridge, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Cancer Research UK Cambridge Cancer Center, Cambridge</wicri:regionArea>
<wicri:noRegion>Cambridge</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Frohling, Stefan" sort="Frohling, Stefan" uniqKey="Frohling S" first="Stefan" last="Fröhling">Stefan Fröhling</name>
<affiliation wicri:level="3"><nlm:affiliation>German Cancer Consortium, Heidelberg, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Cancer Consortium, Heidelberg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Karlsruhe</region>
<settlement type="city">Heidelberg</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Division of Translational Medical Oncology, National Center for Tumor Diseases Heidelberg and German Cancer Research Center, Heidelberg, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Division of Translational Medical Oncology, National Center for Tumor Diseases Heidelberg and German Cancer Research Center, Heidelberg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Karlsruhe</region>
<settlement type="city">Heidelberg</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="J Ger, Dirk" sort="J Ger, Dirk" uniqKey="J Ger D" first="Dirk" last="J Ger">Dirk J Ger</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Medical Oncology, National Center for Tumor Diseases Heidelberg and Heidelberg University Hospital, Heidelberg, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Medical Oncology, National Center for Tumor Diseases Heidelberg and Heidelberg University Hospital, Heidelberg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Karlsruhe</region>
<settlement type="city">Heidelberg</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Valenza, Franco" sort="Valenza, Franco" uniqKey="Valenza F" first="Franco" last="Valenza">Franco Valenza</name>
<affiliation wicri:level="3"><nlm:affiliation>Università Statale di Milano, Milan, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Università Statale di Milano, Milan</wicri:regionArea>
<placeName><settlement type="city">Milan</settlement>
<region nuts="2">Lombardie</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan</wicri:regionArea>
<placeName><settlement type="city">Milan</settlement>
<region nuts="2">Lombardie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="De Braud, Filippo" sort="De Braud, Filippo" uniqKey="De Braud F" first="Filippo" last="De Braud">Filippo De Braud</name>
<affiliation wicri:level="3"><nlm:affiliation>Università Statale di Milano, Milan, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Università Statale di Milano, Milan</wicri:regionArea>
<placeName><settlement type="city">Milan</settlement>
<region nuts="2">Lombardie</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan</wicri:regionArea>
<placeName><settlement type="city">Milan</settlement>
<region nuts="2">Lombardie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="De Petris, Luigi" sort="De Petris, Luigi" uniqKey="De Petris L" first="Luigi" last="De Petris">Luigi De Petris</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Oncology and Pathology, Karolinska Institutet, Stockholm</wicri:regionArea>
<placeName><settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Theme Cancer, Karolinska University Hospital, Stockholm, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Theme Cancer, Karolinska University Hospital, Stockholm</wicri:regionArea>
<placeName><settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bergh, Jonas" sort="Bergh, Jonas" uniqKey="Bergh J" first="Jonas" last="Bergh">Jonas Bergh</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Oncology and Pathology, Karolinska Institutet, Stockholm</wicri:regionArea>
<placeName><settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Theme Cancer, Karolinska University Hospital, Stockholm, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Theme Cancer, Karolinska University Hospital, Stockholm</wicri:regionArea>
<placeName><settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ernberg, Ingemar" sort="Ernberg, Ingemar" uniqKey="Ernberg I" first="Ingemar" last="Ernberg">Ingemar Ernberg</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Stockholm, Sweden.</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Stockholm</wicri:regionArea>
<placeName><settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
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<author><name sortKey="Besse, Benjamin" sort="Besse, Benjamin" uniqKey="Besse B" first="Benjamin" last="Besse">Benjamin Besse</name>
<affiliation wicri:level="3"><nlm:affiliation>Gustave Roussy Cancer Campus, Villejuif, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Gustave Roussy Cancer Campus, Villejuif</wicri:regionArea>
<placeName><settlement type="city">Villejuif</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Barlesi, Fabrice" sort="Barlesi, Fabrice" uniqKey="Barlesi F" first="Fabrice" last="Barlesi">Fabrice Barlesi</name>
<affiliation wicri:level="3"><nlm:affiliation>Gustave Roussy Cancer Campus, Villejuif, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Gustave Roussy Cancer Campus, Villejuif</wicri:regionArea>
<placeName><settlement type="city">Villejuif</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Aix Marseille University, CNRS, INSERM, CRCM, Marseille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Aix Marseille University, CNRS, INSERM, CRCM, Marseille</wicri:regionArea>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Garralda, Elena" sort="Garralda, Elena" uniqKey="Garralda E" first="Elena" last="Garralda">Elena Garralda</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Medical Oncology, Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology, Barcelona, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Department of Medical Oncology, Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology, Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Piris Gimenez, Alejandro" sort="Piris Gimenez, Alejandro" uniqKey="Piris Gimenez A" first="Alejandro" last="Piris-Giménez">Alejandro Piris-Giménez</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Medical Oncology, Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology, Barcelona, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Department of Medical Oncology, Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology, Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Baumann, Michael" sort="Baumann, Michael" uniqKey="Baumann M" first="Michael" last="Baumann">Michael Baumann</name>
<affiliation wicri:level="3"><nlm:affiliation>German Cancer Consortium, Heidelberg, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Cancer Consortium, Heidelberg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Karlsruhe</region>
<settlement type="city">Heidelberg</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>German Cancer Research Center, Heidelberg, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>German Cancer Research Center, Heidelberg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Karlsruhe</region>
<settlement type="city">Heidelberg</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Apolone, Giovanni" sort="Apolone, Giovanni" uniqKey="Apolone G" first="Giovanni" last="Apolone">Giovanni Apolone</name>
<affiliation wicri:level="3"><nlm:affiliation>Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan</wicri:regionArea>
<placeName><settlement type="city">Milan</settlement>
<region nuts="2">Lombardie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Soria, Jean Charles" sort="Soria, Jean Charles" uniqKey="Soria J" first="Jean Charles" last="Soria">Jean Charles Soria</name>
<affiliation wicri:level="3"><nlm:affiliation>Gustave Roussy Cancer Campus, Villejuif, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Gustave Roussy Cancer Campus, Villejuif</wicri:regionArea>
<placeName><settlement type="city">Villejuif</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Tabernero, Josep" sort="Tabernero, Josep" uniqKey="Tabernero J" first="Josep" last="Tabernero">Josep Tabernero</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Medical Oncology, Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology, Barcelona, Spain.</nlm:affiliation>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Department of Medical Oncology, Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology, Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Caldas, Carlos" sort="Caldas, Carlos" uniqKey="Caldas C" first="Carlos" last="Caldas">Carlos Caldas</name>
<affiliation wicri:level="1"><nlm:affiliation>Cancer Research UK Cambridge Cancer Center, Cambridge, UK. carlos.caldas@cruk.cam.ac.uk.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Cancer Research UK Cambridge Cancer Center, Cambridge</wicri:regionArea>
<wicri:noRegion>Cambridge</wicri:noRegion>
</affiliation>
<affiliation wicri:level="4"><nlm:affiliation>Department of Oncology and Cancer Research UK Cambridge Institute, Li Ka Shing Center, University of Cambridge, Cambridge, UK. carlos.caldas@cruk.cam.ac.uk.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Oncology and Cancer Research UK Cambridge Institute, Li Ka Shing Center, University of Cambridge, Cambridge</wicri:regionArea>
<orgName type="university">Université de Cambridge</orgName>
<placeName><settlement type="city">Cambridge</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Angleterre de l'Est</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Voest, Emile E" sort="Voest, Emile E" uniqKey="Voest E" first="Emile E" last="Voest">Emile E. Voest</name>
<affiliation wicri:level="3"><nlm:affiliation>Division of Molecular Oncology & Immunology, The Netherlands Cancer Institute, Amsterdam, the Netherlands. e.voest@nki.nl.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Division of Molecular Oncology & Immunology, The Netherlands Cancer Institute, Amsterdam</wicri:regionArea>
<placeName><settlement type="city">Amsterdam</settlement>
<region nuts="2" type="province">Hollande-Septentrionale</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:affiliation>Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands. e.voest@nki.nl.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">Pays-Bas</country>
<wicri:regionArea>Oncode Institute, The Netherlands Cancer Institute, Amsterdam</wicri:regionArea>
<placeName><settlement type="city">Amsterdam</settlement>
<region nuts="2" type="province">Hollande-Septentrionale</region>
</placeName>
</affiliation>
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<series><title level="j">Nature medicine</title>
<idno type="eISSN">1546-170X</idno>
<imprint><date when="2020" type="published">2020</date>
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<term>Betacoronavirus (MeSH)</term>
<term>Coronavirus Infections (complications)</term>
<term>Coronavirus Infections (epidemiology)</term>
<term>Coronavirus Infections (prevention & control)</term>
<term>Delivery of Health Care (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Neoplasms (complications)</term>
<term>Neoplasms (therapy)</term>
<term>Pandemics (prevention & control)</term>
<term>Pneumonia, Viral (complications)</term>
<term>Pneumonia, Viral (epidemiology)</term>
<term>Pneumonia, Viral (prevention & control)</term>
</keywords>
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<term>Humains (MeSH)</term>
<term>Infections à coronavirus (complications)</term>
<term>Infections à coronavirus (prévention et contrôle)</term>
<term>Infections à coronavirus (épidémiologie)</term>
<term>Pandémies (prévention et contrôle)</term>
<term>Pneumopathie virale (complications)</term>
<term>Pneumopathie virale (prévention et contrôle)</term>
<term>Pneumopathie virale (épidémiologie)</term>
<term>Prestations des soins de santé (MeSH)</term>
<term>Soins ambulatoires (statistiques et données numériques)</term>
<term>Tumeurs (complications)</term>
<term>Tumeurs (thérapie)</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Coronavirus Infections</term>
<term>Neoplasms</term>
<term>Pneumonia, Viral</term>
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<term>Pneumonia, Viral</term>
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<term>Pandemics</term>
<term>Pneumonia, Viral</term>
</keywords>
<keywords scheme="MESH" qualifier="prévention et contrôle" xml:lang="fr"><term>Infections à coronavirus</term>
<term>Pandémies</term>
<term>Pneumopathie virale</term>
</keywords>
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</keywords>
<keywords scheme="MESH" qualifier="statistiques et données numériques" xml:lang="fr"><term>Soins ambulatoires</term>
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<term>Pneumopathie virale</term>
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<term>Delivery of Health Care</term>
<term>Humans</term>
</keywords>
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<term>Humains</term>
<term>Infections à coronavirus</term>
<term>Pneumopathie virale</term>
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<front><div type="abstract" xml:lang="en">The current COVID-19 pandemic challenges oncologists to profoundly re-organize oncological care in order to dramatically reduce hospital visits and admissions and therapy-induced immune-related complications without compromising cancer outcomes. Since COVID-19 is a novel disease, guidance by scientific evidence is often unavailable, and impactful decisions are inevitably made on the basis of expert opinions. Here we report how the seven comprehensive cancer centers of Cancer Core Europe have organized their healthcare systems at an unprecedented scale and pace to make their operations 'pandemic proof'. We identify and discuss many commonalities, but also important local differences, and pinpoint critical research priorities to enable evidence-based remodeling of cancer care during the COVID-19 pandemic. Also, we discuss how the current situation offers a unique window of opportunity for assessing the effects of de-escalating anticancer regimens, which may fast-forward the development of more-refined and less-toxic treatments. By sharing our joint experiences, we offer a roadmap for proceeding and aim to mobilize the global research community to generate the data that are critically needed to offer the best possible care to patients.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">32405058</PMID>
<DateCompleted><Year>2020</Year>
<Month>05</Month>
<Day>18</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>05</Month>
<Day>28</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1546-170X</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>26</Volume>
<Issue>5</Issue>
<PubDate><Year>2020</Year>
<Month>05</Month>
</PubDate>
</JournalIssue>
<Title>Nature medicine</Title>
<ISOAbbreviation>Nat. Med.</ISOAbbreviation>
</Journal>
<ArticleTitle>Caring for patients with cancer in the COVID-19 era.</ArticleTitle>
<Pagination><MedlinePgn>665-671</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1038/s41591-020-0874-8</ELocationID>
<Abstract><AbstractText>The current COVID-19 pandemic challenges oncologists to profoundly re-organize oncological care in order to dramatically reduce hospital visits and admissions and therapy-induced immune-related complications without compromising cancer outcomes. Since COVID-19 is a novel disease, guidance by scientific evidence is often unavailable, and impactful decisions are inevitably made on the basis of expert opinions. Here we report how the seven comprehensive cancer centers of Cancer Core Europe have organized their healthcare systems at an unprecedented scale and pace to make their operations 'pandemic proof'. We identify and discuss many commonalities, but also important local differences, and pinpoint critical research priorities to enable evidence-based remodeling of cancer care during the COVID-19 pandemic. Also, we discuss how the current situation offers a unique window of opportunity for assessing the effects of de-escalating anticancer regimens, which may fast-forward the development of more-refined and less-toxic treatments. By sharing our joint experiences, we offer a roadmap for proceeding and aim to mobilize the global research community to generate the data that are critically needed to offer the best possible care to patients.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>van de Haar</LastName>
<ForeName>Joris</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Division of Molecular Oncology & Immunology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Division of Molecular Carcinogenesis, The Netherlands Cancer Institute, Amsterdam, the Netherlands.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Hoes</LastName>
<ForeName>Louisa R</ForeName>
<Initials>LR</Initials>
<AffiliationInfo><Affiliation>Division of Molecular Oncology & Immunology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Coles</LastName>
<ForeName>Charlotte E</ForeName>
<Initials>CE</Initials>
<AffiliationInfo><Affiliation>Cancer Research UK Cambridge Cancer Center, Cambridge, UK.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Seamon</LastName>
<ForeName>Kenneth</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>Cancer Research UK Cambridge Cancer Center, Cambridge, UK.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Fröhling</LastName>
<ForeName>Stefan</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>German Cancer Consortium, Heidelberg, Germany.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Division of Translational Medical Oncology, National Center for Tumor Diseases Heidelberg and German Cancer Research Center, Heidelberg, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Jäger</LastName>
<ForeName>Dirk</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>Department of Medical Oncology, National Center for Tumor Diseases Heidelberg and Heidelberg University Hospital, Heidelberg, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Valenza</LastName>
<ForeName>Franco</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Università Statale di Milano, Milan, Italy.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>de Braud</LastName>
<ForeName>Filippo</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Università Statale di Milano, Milan, Italy.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>De Petris</LastName>
<ForeName>Luigi</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Theme Cancer, Karolinska University Hospital, Stockholm, Sweden.</Affiliation>
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<AffiliationInfo><Affiliation>Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Theme Cancer, Karolinska University Hospital, Stockholm, Sweden.</Affiliation>
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<Initials>I</Initials>
<AffiliationInfo><Affiliation>Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Stockholm, Sweden.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Besse</LastName>
<ForeName>Benjamin</ForeName>
<Initials>B</Initials>
<AffiliationInfo><Affiliation>Gustave Roussy Cancer Campus, Villejuif, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Barlesi</LastName>
<ForeName>Fabrice</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Gustave Roussy Cancer Campus, Villejuif, France.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Aix Marseille University, CNRS, INSERM, CRCM, Marseille, France.</Affiliation>
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<Initials>E</Initials>
<AffiliationInfo><Affiliation>Department of Medical Oncology, Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology, Barcelona, Spain.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Piris-Giménez</LastName>
<ForeName>Alejandro</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Department of Medical Oncology, Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology, Barcelona, Spain.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Baumann</LastName>
<ForeName>Michael</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>German Cancer Consortium, Heidelberg, Germany.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>German Cancer Research Center, Heidelberg, Germany.</Affiliation>
</AffiliationInfo>
</Author>
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<ForeName>Giovanni</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy.</Affiliation>
</AffiliationInfo>
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<ForeName>Jean Charles</ForeName>
<Initials>JC</Initials>
<AffiliationInfo><Affiliation>Gustave Roussy Cancer Campus, Villejuif, France.</Affiliation>
</AffiliationInfo>
</Author>
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<ForeName>Josep</ForeName>
<Initials>J</Initials>
<Identifier Source="ORCID">http://orcid.org/0000-0002-2495-8139</Identifier>
<AffiliationInfo><Affiliation>Department of Medical Oncology, Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology, Barcelona, Spain.</Affiliation>
</AffiliationInfo>
</Author>
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<ForeName>Carlos</ForeName>
<Initials>C</Initials>
<Identifier Source="ORCID">http://orcid.org/0000-0003-3547-1489</Identifier>
<AffiliationInfo><Affiliation>Cancer Research UK Cambridge Cancer Center, Cambridge, UK. carlos.caldas@cruk.cam.ac.uk.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Oncology and Cancer Research UK Cambridge Institute, Li Ka Shing Center, University of Cambridge, Cambridge, UK. carlos.caldas@cruk.cam.ac.uk.</Affiliation>
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<ForeName>Emile E</ForeName>
<Initials>EE</Initials>
<Identifier Source="ORCID">http://orcid.org/0000-0001-8249-9586</Identifier>
<AffiliationInfo><Affiliation>Division of Molecular Oncology & Immunology, The Netherlands Cancer Institute, Amsterdam, the Netherlands. e.voest@nki.nl.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Oncode Institute, The Netherlands Cancer Institute, Amsterdam, the Netherlands. e.voest@nki.nl.</Affiliation>
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<Month>04</Month>
<Day>16</Day>
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<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Nat Med</MedlineTA>
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<CommentsCorrectionsList><CommentsCorrections RefType="CommentIn"><RefSource>J Plast Reconstr Aesthet Surg. 2020 Jul;73(7):1357-1404</RefSource>
<PMID Version="1">32487361</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="ErratumIn"><RefSource>Nat Med. 2020 Jul;26(7):1146</RefSource>
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<MeshHeading><DescriptorName UI="D003695" MajorTopicYN="N">Delivery of Health Care</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009369" MajorTopicYN="Y">Neoplasms</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName>
<QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName>
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<Month>04</Month>
<Day>04</Day>
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<PubMedPubDate PubStatus="accepted"><Year>2020</Year>
<Month>04</Month>
<Day>06</Day>
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<settlement><li>Amsterdam</li>
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<li>Heidelberg</li>
<li>Marseille</li>
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<country name="Royaume-Uni"><noRegion><name sortKey="Coles, Charlotte E" sort="Coles, Charlotte E" uniqKey="Coles C" first="Charlotte E" last="Coles">Charlotte E. Coles</name>
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<country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Frohling, Stefan" sort="Frohling, Stefan" uniqKey="Frohling S" first="Stefan" last="Fröhling">Stefan Fröhling</name>
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<country name="Suède"><region name="Svealand"><name sortKey="De Petris, Luigi" sort="De Petris, Luigi" uniqKey="De Petris L" first="Luigi" last="De Petris">Luigi De Petris</name>
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<country name="Espagne"><region name="Catalogne"><name sortKey="Garralda, Elena" sort="Garralda, Elena" uniqKey="Garralda E" first="Elena" last="Garralda">Elena Garralda</name>
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<name sortKey="Tabernero, Josep" sort="Tabernero, Josep" uniqKey="Tabernero J" first="Josep" last="Tabernero">Josep Tabernero</name>
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   |wiki=    Sante
   |area=    CovidFranceV1
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	Serveur d'exploration sur la COVID en France
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur la COVID en France

Caring for patients with cancer in the COVID-19 era.

Caring for patients with cancer in the COVID-19 era.

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Abstract

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